Abstract

FLORES, Yonny et al. A 5-METHYLCOUMARIN GLUCOSIDE AND A COUMESTAN DERIVATIVE FROM MUTISIA ORBIGNYANA. Rev. Bol. Quim [online]. 2009, vol.26, n.1, pp.21-26. ISSN 0250-5460.

The ethanolic extract of the aerial parts from Mutisia orbignyana afforded two major compounds: mutisifurocoumarin (1) and 5-methylcoumarine-4-β-glucoside (2). The completely assignment of ¹H and 13C NMR data of compound (2) is presented for the first time as well as some reassignments of 13C NMR spectrum for compound (1), applying 2D NMR techniques. In addition, the antiproliferative effect on colon cancer cells (CaCo2) and the scavenging effect using the ABTS test were measured The results showed an interesting scavenging activity and a non proliferative effect on colon cancer cells.

Keywords : Mutisia orbignyana; Compositae; coumarins; antiproliferative capacity; scavenging effect; Bolivian medicinal plants.

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