Abstract

FERNANDEZ FLORES, Nadia Danitza; CALDERON BURGOA, Maria Renne  and  BURGOA CAMPOS, Danitza Diana. BENEFITS OF PLATELET RICH PLASMA IN THE TREATMENT OF CHRONIC DIABETIC FOOT ULCERS. Rev. Méd. La Paz [online]. 2023, vol.29, n.2, pp.86-99.  Epub Dec 30, 2023. ISSN 1726-8958.

Diabetes Mellitus is a chronic disease that affects millions of people around the world, causing socioeconomic and emotional problems; one of the most feared complications of the disease are chronic diabetic foot ulcers (UCPD), since they constitute one of the main causes of lower limb amputation, the highest prevalence was found in North America (13%), in Bolivia the Type 2 diabetes had a national adult prevalence of 6.5%, and approximately 20% of them developed UCPD. Therefore, it was essential to have an effective treatment that prevents chronicity, infection and amputation of the limb affected by ulcers. Platelet-rich plasma (PRP) is a blood-derived product with several elements involved in tissue regeneration and with anti-inflammatory effects on various lesions; For this reason, it emerges as a promising option for the treatment of UCPD regardless of the degree of injury (Wagner grades). To expose its benefits and consider it as first-line treatment, a systematic review was carried out, with descriptive-exploratory objectives; the literature was collected from primary (last 5 years), secondary and tertiary sources. Finally, after analyzing the results, it is concluded that PRP as a treatment decreases the healing time of diabetic foot ulcers, the risk of infection, etc.

Keywords : Chronic ulcers; diabetic foot; platelet-rich plasma; ozone.

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