Abstract

BANCES GARCIA, Fary Betsy; RODRIGUEZ DIAZ, David Rene; ALBUQUERQUE FERNANDEZ, Pablo  and  PAZ MARCHENA, Aldo. Efficacy and safeness Nitazoxanide compared with Albendazole in symptomatic Giardiasis children treatment in Trujillo, Perú 2008 - 2009. Rev Cient Cienc Méd [online]. 2013, vol.16, n.1, pp.6-11. ISSN 1817-7433.

Giardiasis is a public health problem, most prevalent in developing countries associated with poverty and poor health care system with a high condition in children. The objetive was to compare the efficacy and safeness of nitazoxanide and albendazole in the treatment of symptomatic giardiasis in children. The study population consisted on children of both sexes who attended the General Medicine Clinic Funegra Medical Center of Trujillo whose age ranged between 3-14 years old with confirmed diagnosis of giardiasis, divided into two groups: those who received treatment A (Albendazole) and those with treatment B (Nitazoxanide) and who obey the inclusion and exclusion criteria established. The mean age for group A was 6.73 and 3.01 in group B, 7.04 3.05. Clinical manifestations at the beginning of treatment regimen were led by abdominal pain. There was a higher rate of clinical resolution and coproparasitologic for nitazoxanide group, there was no statistically significant difference in this aspect with respect to the albendazole group. Nitazoxanide showed higher percentage of side effects than Albendazole. It was concluted that Albendazole and nitazoxanide proved to be effective and safe in the treatment of symptomatic giardiasis in children. The efficacy of albendazole was 93,8%. The efficacy of nitazoxanide was 96,9%. The main adverse effects were abdominal pain, decreased appetite and diarrhea, abdominal pain was more frequent in the group Nitazoxanide.

Keywords : Giardiasis; treatment; efficacy.

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