Abstract

BARBECHO CORAISACA, Diana Verónica. Antimicrobial susceptibility in Pseudomona spp., in the General Teaching Hospital Cuenca-Ecuador. Vive Rev. Salud [online]. 2021, vol.4, n.12, pp.50-65. ISSN 2664-3243.  https://doi.org/10.33996/revistavive.v4i12.108.

Pseudomonas aeruginosa is a nosocomial pathogen par excellence; the appearance of multidrug resistant (MDR) and extreme drug resistant (XDR) strains is becoming more frequent and is causing great concern; the indiscriminate use of antibiotics has caused this situation. The objective of this study was to know the different resistance profiles presented by the isolated objects of study according to their origin, either at the intrahospital level or of community origin, in addition to characterizing the main resistance mechanisms and antibiotypes. The present investigation was of a documentary, descriptive, cross-sectional type, for which the accumulated susceptibility data reported by the microbiology department of the General Teaching Hospital from January 2015 to December 2019 was used. It was found that in this hospital there is a higher prevalence of resistance to aminoglycosides (20-25%), fluoroquinolones (22-25%) and carbapenems (19-21%); being P. aeruginosa the most prevalent species. Regarding the type of carbapenemases that are of clinical interest due to their limiting therapeutic option, a strain with a phenotype compatible with metallobetalamase was identified, it is presumed that the predominant resistance mechanism was impermeability. No PDR strains were identified, but 21.6% were shown with an MDR profile, isolated mainly in hospital services as well as the XDR strains.

Keywords : Pseudomonas; Antibiotic Resistance; Carbapenem; Antibiotic Sensitivity.

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