Abstract

VILLALTA, José David Andrade; GONZALEZ, Andrés Felipe Mercado; NARVAEZ, Margarita Rosa Aveiga  and  AUCAY, Homero Abel Chacho. Vagus nerve stimulation in refractory epilepsy and previous callosotomy without vimprovement. Case report. Vive Rev. Salud [online]. 2023, vol.6, n.16, pp.116-128.  Epub Feb 14, 2023. ISSN 2664-3243.  https://doi.org/10.33996/revistavive.v6i16.211.

Refractory epilepsy, both generalized and focal, is an extremely disabling pathology. For its treatment, callosotomy has been established for decades as the first surgical line for its control, which can present important side effects such as disconnection and loss syndrome. by heart, however, there are patients who do not respond to callosotomy and need new lines of treatment, looking for an answer to their condition in vagus nerve stimulation. Description of the case study. We present the case of a 24-year-old male patient with a pathological history of generalized tonic-clonic seizures confirmed by a 24-hour video electroencephalogram, predominantly nocturnal for 13 years, undergoing 2 different antiepileptic pharmacological mechanisms over a period of 7 years in duration, later diagnosed with refractory epilepsy, for which callosotomy was performed without control of its clinical picture, the same year vagus nerve stimulation was performed, presenting favorable results in its evolution. Conclution. After evidencing the present case study, it is concluded that the treatment of refractory epilepsy with the placement of a left vagus nerve stimulator associated with a correct AED regimen is a very effective alternative to consider in these patients.

Keywords : Anticonvulsants; Corpus Callosum; Drug Resistant Epilepsy; Vagus Nerve Stimulation; Case Reports; Drug Resistance; Epilepsy.

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