Revista CON-CIENCIA
versión impresa ISSN 2310-0265
Resumen
QUISPE CABANA, Yhissel Zuleyca y SOTO SANCHEZ, María Luz. Frequency of toxoplasmosis and its relationship with the clinical diagnosis of patients attending the SELADIS Institute between January 2021 and July 2022. Rev.Cs.Farm. y Bioq [online]. 2023, vol.11, n.2, pp.57-71. ISSN 2310-0265. https://doi.org/10.53287/fgof8540jh68p.
Introduction
. Toxoplasmosis is a parasitic zoonosis disease that affects humans and many other vertebrate species, and is caused by the etiological agent known as Toxoplasma gondii.
Objective
. The aim of this study is to determine the frequency of toxoplasmosis in samples from patients who were assisted in the SELADIS Institute (*) in the period between January 2021 and July 2022, in addition to its relation to the clinical diagnosis including requested tests.
Materials and methods
. 290 samples from patients were considered that also required IgG and IgM anti-Toxoplasma gondii antibodies, using an ELISA assay (commercial kit).
Results.
The frequency of IgM antibodies against T. gondii was 7.24% (21/290) and IgG antibodies against T. gondii were 33.1% (96/290). In relation to age, it was observed that in adult patients (over 31 years of age) the frequency was higher (IgM: 4.14%, IgG: 23.8%). 6.9% of the patients had a diagnosis related to ocular pathology, 6.21% were pregnant women and among them the seropositivity for IgG antibodies was 24.64%; and for IgM it was 8.70% (first trimester 2.90% and second 4.35%). The seropositivity for IgG antibodies in kidney transplant patients was 1.4% and 0% for IgM. In patients with adenomegaly, 2.4% were positive for IgG and 0.69% for IgM.
Conclusion
. In conclusion, it was found that the frequency of antibodies against Toxoplasmosis in the study population was 33.1% for IgG and 7.24% for IgM. In relation to clinical diagnosis, it was found that the three main health scenarios are (in descending order of importance), for IgG Ab against toxoplasmosis: ocular pathology, pregnancy and adenomegaly. Besides this, it was found that the relation of these three scenarios diagnoses to IgM Ab against toxoplasmosis are: pregnancy, ocular pathology and adenomegaly.
Palabras clave : Toxoplasmosis; Pregnancy; Eye damage; Adenomegaly; ELISA.