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Gaceta Médica Boliviana
versão On-line ISSN 1012-2966
Resumo
MARTINEZ-OLIVA, Brenda Gisela et al. Sensitivity and specificity of inmunocromatographic tests used in the new algorithm of HIV diagnosis in Bolivia. Gac Med Bol [online]. 2018, vol.41, n.2, pp.06-08. ISSN 1012-2966.
Objective: to evaluate the sensitivity and specificity of the two rapid tests used in the new algorithm of HIV diagnosis in Bolivia, Alere DetermineTM HIV 1/2 as a screening test and Uni-Gold TM HIV as a confirmatory test. Methods: this is a descriptive and non-experimental study. Sixty serum samples were used with reactive results for HIV from different health establishments in Cochabamba sent to LABIMED from January to June 2016 for HIV confirmation. The 60 samples (27 positive and 33 negative for HIV) were tested with Alere DetermineTM HIV 1/2 and Uni-GoldTM HIV. Results: Alere DetermineTM HIV 1/2 presented a sensitivity of 100 % and a specificity of 54,5%. Uni-GoldTM HIV reported a sensitivity of 92,6% and a specificity of 97%. Conclusions: the sensitivity of Alere Determine TM HIV 1/2 fulfilled the criteria of the Ministry of Health and Sports of Bolivia (rapid screening test must have a sensitivity ≥ 99.8%). The specificity of Uni-GoldTM HIV in this study did not fulfill the Ministry’s specificity criterion (rapid confirmation test must have a specificity ≥99.9%).
Palavras-chave : HIV antibodies; early diagnosis; AIDS serodiagnosis; inmunologic tests; sensitivity and specificity; algorithm.