Resumo

SOTO VAZQUEZ, Ramón et al. PHARMACOLOGICAL AND INTELLECTUAL PROPERTY CONSIDERATIONS FOR THE DEVELOPMENT OF DRUGS USED IN THE COVID-19 TREATMENT. Rev. Cien. Tec. In. [online]. 2021, vol.19, n.23, pp.11-88. ISSN 2225-8787.

ABSTRACT The SARS-CoV-2 infection has generated serious health problems for humanity, as it is an infectious disease caused by a new etiological agent and there is still no a specific treatment. Thanks to the joint efforts of the entire scientific society, it has been possible to identify the virus, its genomic structure and how the COVID-19 infection develops in diagnosed patients. Due to continuous research, the pharmaceutical industry offers molecules whose pharmacological activity is partially positive not only for the main symptoms treatment at different stages of COVID-19 infection, but also for the complications occurred in patients, if treated early. This article presents a review of the most used molecules for the COVID-19 treatment with the purpose of providing a guide on the use feasibility of the known-molecules that are used for this disease. This involves a consolidated bibliography of information available so far on what it is known about COVID-19 and the active ingredients that act effectively. Special emphasis is placed on the physicochemical properties and the activeingredients structure in terms of providing guidelines for possible treatments in COVID-19 infection. In addition, an opinion review on the patents related to the aforementioned active ingredients is included for highlighting the facility of their possible uses or modifications on their formulations.

Palavras-chave : Covid,; Patents; Treatment; Generic; Biotech; SARS1.

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