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Vive Revista de Salud
versão impressa ISSN 2664-3243
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MARQUEZ LANCHE, Maricela Magaly e PRIETO FUENTEMAYOR, Carem. Noninvasive methods on diagnosis of nonalcoholic hepatic steatosis: description of their sensitivity and specificity. Vive Rev. Salud [online]. 2022, vol.5, n.13, pp.214-232. Epub 27-Maio-2022. ISSN 2664-3243. https://doi.org/10.33996/revistavive.v5i13.143.
Non-alcoholic fatty liver disease is a pathology of worldwide distribution, being its chronic hepatic evolution the most common. The research aims to update and describe the sensitivity and specificity of noninvasive methods for the diagnosis of hepatic steatosis, prioritizing the biochemical tests used for NAFLD, applying a documentary approach through a systematic review, and using as methodology the PRISMA standards and the QUADAS-2 tool for the filter and selection of articles. In total, 441 articles related to the research topic were obtained through databases such as PubMed, Scopus, Web of Science, Science Direct, Scielo and others, of which 13 were selected. It was found that factors related to the presence or not of comorbidities such as metabolic syndrome, diabetes, AHT, ethnicity, weight, and race influence NAFLD; on the other hand, liver enzymes are not sensitive predictors of the disease. It is also evidenced that hepatic steatosis is directly related to increased BMI, triglycerides, HDL, ALT and GGT.
Palavras-chave : NAFLD; Nonalcoholic fatty liver; Non-invasive methods; biomarkers.